Table 2.
Recruitment TST size | Recruitment TST positivity | Follow-up increase in TST size | Follow-up TST conversion | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate regression (N = 174) | Multiple regression (N = 166) | Univariate regression (N = 174) | Multiple regression (N = 166) | Univariate regression (N = 63) | Multiple regression (N = 52) | Univariate regression (N = 63) | Multiple regression (N = 56) | |||||||||
Co. | P value | Co. | P value | OR | P value | OR | P value | Co. | P value | Co. | P value | OR | P value | OR | P value | |
Data collected at recruitment | ||||||||||||||||
Age | 0.2 | 0.001 | 0.012 | 0.001 | 1.0 | 0.07 | 1.02 | 0.1 | 0.006 | 0.8 | −0.0079 | 0.8 | 1.0 | 0.4 | 1.03 | 0.3 |
Gender | −0.001 | 1.0 | −0.0023 | 1.0 | 1.0 | 0.9 | 0.995 | 1.0 | −0.02 | 0.9 | 0.39 | 0.7 | 1.5 | 0.5 | 1.1 | 0.9 |
BCG scars | 0.3 | 0.005 | 0.29 | 0.009 | 2.7 | 0.03 | 2.4 | 0.01 | −0.48 | 0.7 | −1.2 | 0.2 | 0.1 | 0.05 | 0.1 | 0.039 |
Known TB contact | 0.28 | 0.05 | 0.30 | 0.03 | 2.0 | 0.07 | 2.4 | 0.041 | −0.3 | 0.2 | – | – | 0.6 | 0.6 | – | – |
Body mass index | 0.003 | 0.8 | – | – | 1.0 | 0.7 | – | – | 0.02 | 0.2 | 0.21 | 0.1 | 1.2 | 0.09 | – | – |
Percent body fat | 0.007 | 0.2 | – | – | 1.0 | 0.7 | – | – | 0.03 | 0.6 | – | – | 0.03 | 0.6 | – | – |
Intestinal helminth infection* | −0.08 | 0.8 | – | – | 1.7 | 0.6 | – | – | 0.3 | 0.6 | – | – | – | – | – | – |
Intestinal helminth co-infection | −0.11 | 0.4 | – | – | 0.6 | 0.2 | – | – | 0.09 | 0.9 | – | – | 2.1 | 0.3 | – | – |
Data collected at follow-up | ||||||||||||||||
Albendazole vs. placebo | NA | NA | NA | NA | NA | NA | NA | NA | 0.2 | 0.8 | – | – | 1.1 | 0.9 | – | – |
Cure of helminths | NA | NA | NA | NA | NA | NA | NA | NA | −0.1 | 0.5 | – | – | 0.6 | 0.6 | – | – |
Cure/reduction in egg concentration | NA | NA | NA | NA | NA | NA | NA | NA | −0.2 | 0.1 | – | – | 0.5 | 0.3 | – | – |
NA signifies that the analysis was not biologically appropriate, and – signifies that the variable did not feature in the multiple regression model (see Methods). Co = coefficient; OR = odds ratio.
This information could not be included in some analyses in which all participants with available data had intestinal helminth infection.