Table 3.

Efficacy of meglumine antimoniate and miltefosine according to the species of parasite, anatomic location, number and type of lesions and geographic location of infection

Characteristic	Efficacy/total volunteers (%)	P*	Efficacy/total volunteers (%)	P*
	Meglumine antimoniate		Miltefosine
Overall efficacy	103/143 (72)	–	85/145 (58.6)	–
Species
L. (V.) panamensis	23/32 (71.9)	0.5	18/30 (60)	0.3
L. (V.) braziliensis	34/52 (65.4)		25/51 (49)
Number of lesions
1	72/97 (74.2)	0.4	60/101 (59.4)	0.5
2 or more	31/46 (67.4)		24/44 (54.5)
Anatomic location of the lesions
upper part of the body	87/118 (73.7)	0.4	66/117 (56.4)	0.7
lower part of the body	10/17 (58.8)		13/20 (65)
upper and lower body parts	6/8 (75)		5/8 (62.5)
Type of lesion
Nodule	6/7 (85.7)	1	5/9 (55.5)	1
Ulcerated	134/167 (80.2)		90/161 (55.9)
Geographic location of infection
NE	9/17 (52.9)	0.06	10/15 (66.6)	0.5
SE	94/126 (74.6)		74/130 (56.9)

^*χ² test.