Skip to main content
. 2010 Aug 5;83(2):357–364. doi: 10.4269/ajtmh.2010.10-0156

Table 2.

Dosage of liposomal amphotericin B received and apparent adverse events experienced during the 10-day treatment course among study cohort patients at Sadar District Hospital, Vaishali District, India (July 2007 to May 2008; N = 251)

Variables N (%)
Number of doses received of liposomal amphotericin B
Two doses (10 mg/kg) 1 (0.4)
Three doses (15 mg/kg) 4 (1.6)
Four doses (20 mg/kg) 246 (98.0)
Apparent adverse event(s) experienced
No 129 (51.4)
Yes 122 (48.6)
Apparent adverse event experienced*
Muscle-skeletal system
Back pain 2 (0.8)
Digestive system
Nausea and vomiting 25 (10.0)
Diarrhea 20 (8.0)
Dyspepsia 12 (4.8)
Jaundice 2 (0.8)
Respiratory system
Upper respiratory infection 39 (15.5)
Pneumonia 16 (6.4)
Coagulation system
Epistaxis 3 (1.2)
Skin and appendages
Rash 4 (1.6)
Urinary tract infection 4 (1.6)
Unspecified infections 6 (2.4)
Apparent adverse event during infusion
Chills/rigor 8 (3.2)
Severe lip swelling 3 (1.2)
*

One or more symptoms recorded for each patient.

Includes cough and sore throat only.