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. 2010 Apr 19;588(Pt 12):2205–2218. doi: 10.1113/jphysiol.2010.187674

Figure 7. Functional analysis of mutant AQP2 in coexpression studies.

Figure 7

cRNA (5 ng) for either K228E (A) or V24A (B) was injected along with increasing concentrations of R187C cRNA (0–10 ng) and water permeability was evaluated using a 20 mosmol l−1 hyposmotic shock. Pf values are given in 10−4 cm s−1 and represent 7–8 determinations for each condition. Asterisks indicate statistical significance (P < 0.05) in comparison to pure K228E or V24A values while # indicates non-significance compared to controls (P < 0.05). Data are representative of three individual assays.