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. 2010 Apr 27;18(7):1346–1356. doi: 10.1038/mt.2010.61

Figure 4.

Figure 4

Lack of tumorigenicity of phiC31 integrase–modified cord-lining epithelial cells (CLECs) in SCID mice. Immunostaining with antihuman vimentin antibody shows renal subcapsular engraftment of CLECs (a) 1 month and (b) 3 months after implantation in SCID mice. (c) Engraftment of CLECs, 1 month after injection into nuchal subcutaneous region. Original magnification ×200. (d) Immunostaining of cultured CLECs from explants recovered from subcutaneous regions of mice 1 month after implantation. Original magnification ×100. Bar = 100 µm.