Figure 2.

Liver and spleen transduction efficiency. X-gal histochemistry of the (a–h) liver or (i–p) spleen 48 hours following injection of various doses of HDΔ28E4LacZ into mice pretreated 30 minutes prior with either saline or VIP (10 nmol/mouse) by intraperitoneal injection. The results from one representative mouse from each treatment group is shown (n ≥ 5 per treatment). The liver and spleen shown for each treatment condition are from the same mouse. VIP, vasoactive intestinal peptide; vp, vector particles.