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. 2010 Jun 2;285(31):23590–23597. doi: 10.1074/jbc.M110.139469

FIGURE 3.

FIGURE 3.

MTA1 new modifier of NF-κB signaling in stimulated macrophage. A, effect of selective knockdown of MTA1 on the activation status of the NF-κB signaling components in LPS-stimulated Raw cells by Western blot analysis. B, kinase assay for the p-IKKα in LPS-stimulated Raw cells with or without MTA1 knockdown. C, EMSA analysis of the p65·DNA complex in LPS (dark triangles: 0, 30, and 60 min) stimulated Raw cells with or without MTA1 knockdown. D, Western blot analysis for MTA1 in MTA1+/+ and MTA1−/− MEFs. E, effect of LPS on the activation status of NF-κB signaling components in wild-type (WT) and MTA1−/− MEFs by Western blot analysis. F, EMSA analysis of the p65·DNA complex in LPS-stimulated wild-type and MTA1−/− MEFs. Con, control.