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. 2010 May 28;285(31):24228–24237. doi: 10.1074/jbc.M110.133108

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 2. — Dose dependence of resveratrol remodeling of soluble prefibrillar Aβ oligomers. Aβ-soluble oligomers (25 μm; formed after 1 day without agitation) were exposed to various concentrations of resveratrol (Res.) and control solutions for 4 h and monitored via SDS-PAGE (A), dot blots probed with conformation-specific (A11, soluble oligomers) and sequence-specific (6E10) antibodies (B), and cell toxicity analysis (2.5 μm, Aβ, n = 3) (C). Van, vanillin; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.