FIGURE 5.

Templating activity of Aβ conformers. Aβ fibrillar conformers (fibrillar intermediates (Int., A) and amyloid fibrils (B)) were incubated with resveratrol (res., 20 μm) for 0 or 4 h, and their templating activity was evaluated at 25 °C by incubating each insoluble conformer (5 wt % seed) with freshly dissolved Aβ monomers (25 μm) via ThT analysis (n = 5). RFU, relative fluorescence units.