Table 3.
Correlations among clinical features and SOD2 gene expression of primary TSCC†
| Age | Gender | pT stage | pN stage | C stage | Grade | Ki67‡ | SOD2§ |
|---|---|---|---|---|---|---|---|
| Patient cohort # 1 (n = 53) | |||||||
| Age | 0.06 | -0.07 | 0.08 | 0.03 | na | 0.16 | 0.14 |
| Gender | 0.09 | -0.25 | -0.07 | na | 0.01 | 0.20 | |
| pT stage | 0.05 | 0.65 * | na | -0.18 | 0.49 * | ||
| pN stage | 0.49 * | na | 0.21 | -0.28 * | |||
| C stage | na | -0.09 | 0.19 | ||||
| Grade | na | na | |||||
| Ki67 | -0.01 | ||||||
| SOD2 | |||||||
| Patient cohort #2 (n = 100) | |||||||
| Age | 0.12 | -0.05 | -0.10 | -0.01 | -0.01 | -0.01 | -0.16 |
| Gender | 0.11 | 0.04 | 0.11 | 0.07 | -0.05 | -0.02 | |
| pT stage | 0.42 * | 0.77 * | -0.16 | -0.01 | 0.04 | ||
| pN stage | 0.80 * | -0.05 | 0.09 | -0.35 * | |||
| C stage | -0.07 | 0.05 | -0.21 * | ||||
| Grade | 0.05 | -0.30 * | |||||
| Ki67 | -0.28 * | ||||||
| SOD2 | |||||||
† Spearman Correlation Coefficients.
‡ The Ki67 index for Patient Cohort #1 was based on the relative mRNA level. The Ki67 index for Patient Cohort #2 was based on Immunohistochemical analysis.
§ The expression levels of SOD2 for Patient Cohort #1 were based on the relative mRNA level. The expression levels of SOD2 for Patient Cohort #2 were generated from Immunohistochemical analysis.
* p < 0.05. The p values were computed using Fisher's transformed z-score test.
na: data not available.