Table 1.

Filter impact

Filter	# epitopes	# proteins	# combinations
Unfiltered	671,427	20,333	4,196,636
unknown positions filter	671,253	20,333	4,195,788
methionine filter	569,365	20,332	3,839,772
high abundant epitope filter	569,354	20,332	3,312,617
weight filter	559,323	20,178	1,962,034
length filter	530,863	20,020	1,662,437
high abundant protein filter	527,164	20,010	1,598,289

Impact of the different filters applied on the in-silico tryptic digest of the human proteome (Uniprot taxon id 9606), N-C-terminal epitopes of length 4 and 5, Δ_min = 4,