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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Oncogene. 2010 May 24;29(29):4183–4193. doi: 10.1038/onc.2010.165

Figure 1. Cytokinesis failure at an early stage leads to multinucleation in HEK-293 and oral cancer cells.

Figure 1

(A) Examples of successful and failed cytokinesis in UPCI:SCC103 cells as viewed by DIC optics. Arrow head: plasma membrane border between two daughter cells; Arrow: a continuous plasma membrane. Time: hours: minutes; Bar: 10μm (following figures using the same formats). (B) Majority of multinucleated cells are from cytokinesis failure. (C) The frequency of cells with cytokinesis failure by real-time DIC or fluorescence microscopy compared to the frequency of multipolarity.