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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Neurogastroenterol Motil. 2010 Apr 23;22(8):901–e235. doi: 10.1111/j.1365-2982.2010.01505.x

Figure 2.

Figure 2

Cross-inhibition between nAChRs and P2X2 receptors is mediated by the P2X2 receptor C-terminal tail. A. Addition of the GST-control peptide to the intracellular electrode did not alter cross-inhibition between nAChRs and P2X2 receptors. B. Pooled data (n=6) from experiments shown in A. *Indicates significantly different from the predicted sum of currents (P < 0.05). Addition of the GST-P2X2-CT peptide construct (amino acids 365–469) of the P2X2 C-terminal tail to the pipette solution blocks cross-inhibition. D. Pooled data from experiments illustrated in “C” (n=6).