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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Neurogastroenterol Motil. 2010 Apr 23;22(8):901–e235. doi: 10.1111/j.1365-2982.2010.01505.x

Figure 6. Asymmetric constitutive cross-inhibition between nAChRs and P2X2 receptors.

Figure 6

A. Concentration response curves to ACh in cells expressing α3β4 nAChRs alone, and in cells co-expressing α3β4 nAChRs and P2X2 receptors (n=7). P2X2 receptor co-expression caused a parallel rightward shift in the ACh concentration response curve. B. ATP concentration response curves in cells expressing P2X2 receptors alone, and in cells co-expressing α3β4 nAChRs and P2X2 receptors (n=5). nAChR co-expression inhibited responses at low but not high ATP concentrations (see Table 1).