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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Curr Opin Struct Biol. 2010 Apr 8;20(3):262–275. doi: 10.1016/j.sbi.2010.03.001

Figure 1.

Figure 1

Figure 1

Figure 1

Figure 1

G-quadruplex topology and recognition. (a) The potassium-form structure of d(G3T2A)3G3T [19] (2kf7). (b) Groove interactions between distamycin A and the parallel-stranded quadruplex [d(TG4T)]4 [22] (2jt7). (c) Stacking of tetra-substituted naphthalene diimides on the terminal G-tetrads of the parallel-stranded quadruplex [d(TAG3T2AG3T)]2 [24] (3cco). (d) Acridine ligand interactions with the antiparallel-stranded G-quadruplex [d(G4T4G4)]2 [26] (3em2). DNA atoms are colored silver, red, blue and orange for carbon, oxygen, nitrogen and phosphorus, respectively, and carbon atoms of drug molecules are green.