Table 2.

Summary of the demographic and pathophysiological characteristics of the patients included in the model building

Characteristic	Mean ± SD	Range
Age (years)	61.1 ± 16.3	18–85
Total body weight (kg)	73.0 ± 13.3	45–150
Body mass index (kg m−2)	26.2 ± 4.1	18.4–43.8
Apache II score	18.0 ± 6.9	2–41
Serum albumin (g dl−1)	2.3 ± 0.7	0.5–6.2
CrSe (mg dl−1)	1.4 ± 1.0	0.6–5.0
Measured CLCr (ml min−1)	74.7 ± 58.0	10–328
Estimated CLCr (ml min−1)	86.1 ± 55.1	9.5–230.5
PEEP (cm H2O)	7.1 ± 3.0	2–22
FiO2 (%)	49 ± 18	25–100
Fluid balance (ml)	665 ± 1808	−5424/7701
Vancomycin therapy duration (days)	14.7 ± 16.4	1–113
Concentration data per patient (n)	3.0 ± 2.5	1–19

APACHE, Acute Physiology and Chronic Health Evaluation System [17]; Estimated CL_Cr, Creatinine clearance estimated by the Levey method [18]; PEEP, positive end-expiratory pressure; FiO₂, fraction of inspired oxygen.