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. 2009 Jul 31;43(1):26–34. doi: 10.1165/rcmb.2009-0073OC

Figure 5.

Figure 5.

Effects of drugs on actin cytoskeleton, cytochalasin D and jasplakinolide, after a mechanical stretch equivalent to 30% strain. (A) Representative trace of changes in F340/F380 ratio after mechanical stretching, before and after treatment with 0.1 μM cytochalasin D (Cyt D) for 15 min. (B) The F340/F380 ratios in response to stretching in the absence (Control) or presence of 0.1 μM cytochalasin D (Cyt D). (C) Representative trace of changes in F340/F380 ratio before and after treatment with 0.5 μM jasplakinolide for 15 min. (D) The F340/F380 ratios in response to stretching in the absence (control) or presence of 0.5 μM jasplakinolide. Bars represent means ± SD (n = 4). *Significantly different from stretched control values (P < 0.01; two-way, repeated-measures ANOVA with Bonferroni test).