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. 2009 Aug 28;43(1):88–98. doi: 10.1165/rcmb.2008-0480OC

Figure 8.

Figure 8.

Active and total transforming growth factor (TGF)–β1 in the lungs of infant mice. Dams were given doxycycline from the beginning of pregnancy until the pups were killed at PN7. (A) The level of active TGF-β1 was increased in the lungs of IL-1β/β6+/+ and IL-1β/β6−/− mice compared with control/β6+/+ and control/β6−/− mice, respectively. (B) The level of total TGF-β1 did not significantly differ between the genotypes. The level of TGF-β1 was determined by ELISA in lung homogenates from 5–10 animals per group. Data are presented as means (±SEM). *P < 0.05, ***P < 0.001.