Skip to main content
. 2009 Dec 20;2010:386389. doi: 10.4061/2010/386389

Figure 4.

Figure 4

The effects of apigenin and resveratrol on TNF-α-induced expression of ICAM-1, MCP-1, and VCAM-1 in astrocytes isolated from SHRSP/IZM. Dose response: the astrocytes isolated from SHRSP/IZM were washed with FBS-free DMEM, replaced with DMEM containing TNF-α (10 ng/mL), and supplemented with 0, 10, 30, or 50 μM of apigenin (a) or resveratrol (b). They were then incubated for 4 hours. The ICAM-1, MCP-1, and VCAM-1 mRNA measurements were carried out as described in Figure 1 and in the text. The bars represent the mean ± SD (n = 4). Asterisk (*): P < .05 compared with the basal TNF-α value. TNF: TNF-α.