Table 1.
UV-Vis absorption titration parameters for TMPyP4, TMPyP3, and TMPyP2 with four different Bcl2 and C-myc G-quadruplex DNA. Soret band hypochromicity is calculated using the formula: % Hypochromicity = [(€ free − € bound)/€ free] × 100. € free and € bound are the extinction coefficient of free and bound porphyrin, respectively.
| S. No. | Name of quadrupelx DNA and cationic porphyrin | Soret band shift (nm) | Isobestic point (nm) | Percentage hypochromicity |
|---|---|---|---|---|
| 1. | 27Bcl2-TMPyP4 | 423–441 | 435.5 | 59.7% |
| 2. | 27Bcl2-TMPyP3 | 417–431 | 426.5 | 41.5% |
| 3. | 27Bcl2-TMPyP2 | No shift | 422.0 | 23.0% |
| 4. | C-myc-TMPyP4 | 423–439 | 432.2 | 52.3% |
| 5. | C-myc-TMPyP3 | 417–429 | 425.3 | 39.5% |
| 6. | C-myc-TMPyP2 | No shift | 421.7 | 14.7% |