Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Jul 12;190(1):21–24. doi: 10.1083/jcb.201006080

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 Lan and Cleveland

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — Microtubule–kinetochore attachments. Four types of kinetochore–microtubule attachments are highlighted. (A) Monotelic attachment with only one kinetochore attached. Unattached kinetochores produce the mitotic checkpoint inhibitor that delays advance to anaphase by inactivating Cdc20, an activator of the ubiquitin ligase APC/C. (B) Syntelic attachment with both kinetochores attached to microtubules from the same pole. (C) Merotelic attachment with one kinetochore attached to microtubules from both poles. (D) Bioriented attachment (also known as amphitelic) with the two kinetochores of each chromatid pair attached to opposite spindle poles.