Table 2. Pooled data for the in vitro nuclear kinetics of WT GFP–SRY-HMG.
Results are means±S.E.M. for n replicates (where n is indicated in parentheses). Fn/cmax is the maximal nuclear accumulation. P values were calculated using Student's t test with GraphPad Prism 5.0, relative to in the absence of CDZ. NS, not significant.
| Conditions | Fn/cmax (%) | P value |
|---|---|---|
| +Cytosol (3) | 100±0.01 | |
| +Cytosol+70 μM CDZ (3) | 58±4.3 | 0.0006 |
| −Cytosol (5) | 100±0.01 | |
| −Cytosol+35 μM DMSO (3) | 91±33 | NS |
| −Cytosol+35 μM CDZ (3) | 56±19 | 0.0199 |
| −Cytosol+70 μM CDZ (2) | 35±3.9 | <0.0001 |