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. 2010 Jun 3;14(3):R103. doi: 10.1186/cc9047

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Copyright ©2010 Kumpf et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Impact of TIRAP/Mal or TLR4 polymorphisms or their combinations on circulating cytokine levels. Cytokine serum levels (pg/ml) were measured on day 1 after diagnosis of ventilator-associated pneumonia in Group II. Values are shown as median +/- 95% confidence interval (CI) and as mean +/- standard error. Number of patients in each group: Controls = 106, TIRAP/Mal (heterozygotes and homozygotes reported together) = 41, TIRAP/Mal-TLR4 = 3, TLR4 = 9. P values refer to significant differences compared with patients bearing the wild-type for all tested polymorphisms. Comparison calculated with Mann-U Whitney test. In this figure TIRAP/Mal is named TIRAP for readability.