Table 2.
Severity of illness scores, laboratory tests and use of catecholamines during ICU stay
| New-onset AF, no septic shock (n = 26) |
New-onset AF and septic shock (n = 23) |
Maintained SR and septic shock (n = 27) |
P1-value | P2-value | |
|---|---|---|---|---|---|
| Severity of illness scores | |||||
| SOFA max | 8.5 (4-14) | 12 (7-17) | 9 (5-18) | < 0.01 | 0.01 |
| SAPS II | 34 (7-60) | 31 (15-63) | 30 (12-65) | 0.87 | 0.12 |
| Max. CRP level (mg/dl) | 249 (14-339) | 288 (72-483) | 273 (23-412) | 0.04 | 0.28 |
| Use of catecholamines | |||||
| Noradrenaline max. (μg/kg/min) |
0.18 (0.00-1.00) | 0.50 (0.15-2.00) | 0.30 (0.15-1.40 | < 0.01 | 0.13 |
| Noradrenaline at AF (μg/kg/min) | 0.05 (0.00-0.40) | 0.40 (0.03-1.10) | - | < 0.01 | |
| Dobutamine (number of patients) |
2 | 10 | 6 | < 0.01 | 0.14 |
| Serum electrolytes at AF | |||||
| K+ (mval/l) | 4.4 (3.9-5.0) | 4.4 (3.8-5.6) | - | 0.63 | |
| Na+ (mval/l) | 137 (130-163) | 140 (132-161) | - | 0.42 | |
| Ca++ (mval/l) | 1.2 (1.1-1.6) | 1.1 (0.7-1.3) | - | 0.10 | |
Data are given as median (range in parenthesis) or number. P1-value, patients with new-onset atrial fibrillation (AF) without septic shock vs. septic shock patients with new-onset AF; P2-value, septic shock patients with new-onset AF vs. septic shock patients with maintained sinus rhythm (SR).
SOFA max, maximum of the daily calculated sequential organ failure assessment score; SAPS II, simplified acute physiologic score II on admission; Max. CRP level, maximal C-reactive protein level during ICU stay; noradrenaline max, maximal noradrenaline dose during ICU stay; noradrenaline at AF, noradrenaline dose when AF occurred; serum electrolytes at AF, serum electrolyte concentrations when AF occurred.