Table 5.

Creatinine values over time with actual and percent change from baseline by treatment

Creatinine (mg/dL)		Lab values over time				Change from baseline (actual and percent)
		Baseline	Hour 24	Hour 72	Hour 120	to Hour 24		to Hour 72		to Hour 120
100 mg IV Ibuprofen	Average	0.95	0.85	0.85	0.87	-.009	-6.4%	-0.09	-4.1%	-0.08	-1.9%
	SD	0.26	0.21	0.21	0.30	0.23	25.6	0.33	37.0	0.40	48.7
	N	31	30	29	28	30	30	29	29	28	28
	Min	0.57	0.50	0.50	0.50	-0.60	-44.4%	-0.80	-50.0%	-0.90	-56.3%
	Max	1.60	1.40	1.70	2.20	0.50	71.4%	1.00	142.9%	1.50	214.3%
200 mg IV Ibuprofen	Average	0.97	0.85	0.90	0.83	-0.12	-11.4%	-0.07	-6.0%	-0.08	-7.5%
	SD	0.25	0.28	0.29	0.19	0.20	18.3	0.23	19.5	0.17	18.7
	N	30	30	27	24	30	30	27	27	24	24
	Min	0.60	0.11	0.50	0.50	-0.97	-89.8%	-0.60	-37.5%	-0.40	-28.6%
	Max	1.60	1.50	1.70	1.30	0.20	15.4%	0.50	41.7%	0.30	50.0%
400 mg IV Ibuprofen	Average	0.97	0.97	1.07	1.05	0.00	-2.8%	0.11	6.7%	0.06	5.8%
	SD	0.35	0.59	1.05	0.93	0.37	31.7	0.93	88.7	0.86	84.5
	N	31	30	31	27	30	30	31	31	27	27
	Min	0.40	0.30	0.30	0.30	-0.31	-34.1%	-0.30	-30.0%	-0.40	-33.3%
	Max	2.10	3.20	5.81	5.28	1.39	136.3%	4.79	469.6%	4.26	417.6%
Placebo	Average	1.00	0.94	0.86	0.87	-0.06	-5.4%	-0.14	-10.3%	-0.16	-9.8%
	SD	0.44	0.40	0.25	0.23	0.13	12.4	0.26	15.5	0.34	20.4
	N	28	28	28	24	28	28	28	28	24	24
	Min	0.60	0.42	0.50	0.50	-0.30	-33.3%	-1.10	-46.7%	-1.30	-53.3%
	Max	2.80	2.50	1.70	1.50	0.20	18.2%	0.20	25.0%	0.30	37.5%