Table 7.
Platelets (×109/L) | Lab values over time | Change from baseline (actual and percent) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | Hour 24 | Hour 72 | Hour 120 | to Hour 24 | to Hour 72 | to Hour 120 | |||||
100 mg IV Ibuprofen | Average | 222 | 210 | 270 | 325 | -14 | -7% | 40 | 41% | 112 | 109% |
SD | 159 | 164 | 157 | 191 | 43 | 17 | 92 | 69 | 145 | 140 | |
N | 31 | 30 | 28 | 27 | 30 | 30 | 28 | 28 | 27 | 27 | |
Min | 41 | 36 | 73 | 39 | -99 | -41% | -191 | -38% | -169 | -77% | |
Max | 659 | 756 | 690 | 933 | 103 | 20% | 230 | 269% | 473 | 513% | |
200 mg IV Ibuprofen | Average | 190 | 201 | 293 | 416 | 11 | 7% | 101 | 82% | 228 | 188% |
SD | 111 | 127 | 190 | 239 | 63 | 27 | 148 | 99 | 194 | 180 | |
N | 30 | 30 | 26 | 24 | 30 | 30 | 26 | 26 | 24 | 24 | |
Min | 35 | 29 | 102 | 148 | -197 | -56% | -200 | -57% | 3 | 2% | |
Max | 477 | 492 | 965 | 1258 | 205 | 71% | 678 | 412% | 971 | 686% | |
400 mg IV Ibuprofen | Average | 174 | 162 | 229 | 308 | -9 | -6% | 55 | 54% | 136 | 156% |
SD | 116 | 110 | 126 | 149 | 36 | 23 | 103 | 69 | 168 | 161 | |
N | 31 | 30 | 31 | 27 | 30 | 30 | 31 | 31 | 27 | 27 | |
Min | 34 | 20 | 39 | 117 | -87 | -49% | -209 | -41% | -301 | -58% | |
Max | 516 | 464 | 562 | 866 | 115 | 64% | 367 | 243% | 685 | 533% | |
Placebo | Average | 220 | 213 | 268 | 339 | -7 | -4% | 43 | 32% | 127 | 98% |
SD | 124 | 136 | 137 | 137 | 61 | 28 | 84 | 56 | 114 | 122 | |
N | 28 | 28 | 27 | 24 | 28 | 28 | 27 | 27 | 24 | 24 | |
Min | 48 | 5 | 22 | 61 | -163 | -97% | -192 | -87% | -162 | -64% | |
Max | 541 | 448 | 502 | 594 | 130 | 44% | 178 | 213% | 301 | 521% |