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. Author manuscript; available in PMC: 2010 Jul 29.

Published in final edited form as: J Nucl Med. 2010 Apr 15;51(Suppl 1):51S–65S. doi: 10.2967/jnumed.109.068163

TABLE 1. Comparison of Noninvasive Assessment of Atherosclerotic Plaques.

Parameter	MRI	Multicontrast MRI	Dynamic gadolinium-enhanced MRI	USPIO-MRI	¹⁸F-FDG PET/CT	Multidetector CT
Vascular bed	Carotid Aorta Peripheral	Carotid Aorta Peripheral	Carotid Aorta Peripheral	Carotid Peripheral Aorta	Carotid Aorta Peripheral Coronary?	Coronary Carotid Aorta Peripheral

Plaque features	Burden	Composition: lipid-rich/necrotic core (%LR/NC)	Activity/perfusion: Inflammation Neovessels	Activity: Inflammation	Activity: Glucose Inflammation	Burden (characterization?)

Variability (interstudy)	5%–10%	10%	15%	Not applicable	5%–7%	>20%

Medication modulation	3, 6^*, 12 mo	Statins at 18 mo	Not applicable	Statins at 3 mo	Statins at 3 mo	Not applicable

^*

Niacin + statins.

LR = lipid-rich; NC = necrotic.

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