Table 1.

Histological score and osteoclast number

	Synovium	Leukocyte	Cartilage/bone	Osteoclast
Vehicle (n = 6)	2.3 ± 0.8	1.7 ± 0.9	2.7 ± 0.6	62.0 ± 38.6
ZSTK474 (n = 6, 50 mg/kg)	0.0 ± 0.0	0.0 ± 0.0	0.8 ± 0.3	0.3 ± 0.2
P-value	0.009	0.073	0.036	0.024