Table 3.
Multivariate analysis of predictors for radiographic progression
| Variable | OR | 95% CI | P value |
|---|---|---|---|
| Treatment with adalimumaba | 0.21 | 0.10, 0.42 | < 0.001 |
| CRP (continuous) | 1.16 | 1.01, 1.33 | 0.040 |
| CRP > 0.287 mg/dla | 4.31 | 1.42, 13.09 | 0.010 |
| CRP (1.0 mg/dla | 3.28 | 1.66, 6.51 | < 0.001 |
| CRP (2.0 mg/dla | 2.29 | 1.12, 4.69 | 0.023 |
| Modified total Sharp score | 1.01 | 1.00, 1.02 | 0.002 |
CI, confidence interval; CRP, C-reactive protein; OR, odds ratio. Separate multivariate analyses were performed for CRP (continuous), CRP > 0.287 mg/dl, CRP ≥1.0 mg/dl and CRP ≥2.0 mg/dl. For non-CRP variables, results are from the analysis with CRP > 0.287 mg/dl. All multivariate analyses also included baseline age, rheumatoid factor (yes/no), tender joint count, swollen joint count, and methotrexate use (yes/no) as variables; P > 0.05 for each. aDichotomous variables - those without a footnote annotation are continuous variables.