Figure 3.
Proteoglycan incorporation and release during culture in unconditioned, conditioned or conditioned serum with Etanercept (mean +/- SD). Proteoglycan release and incorporation (mean +/- SD) in the presence of unconditioned serum (control, n = 8), conditioned serum (CS, n = 8) or conditioned serum with etanercept (n = 8). (a) Proteoglycan release, (b) Proteogycan incorporation on Day 4, measured by 35SO42- incorporation (n = 8). Results are representative for three separate experiments with different OA cartilage donor - serum donor combinations.