Table 2.
Clinical scores and serum cytokine levels in patients with sufficient and with non-sufficient SF for analysis
| KOOS score | KSCRS score | Baseline serum cytokine levels | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IL-1 | IL-4 | IL-6 | IL-10 | IL-13 | TNFα | IFNγ | OSM | OPG | IL-1ra | |||
| SF available and analysed (14 patients) |
46 (10) |
79 (19) |
0.2 (0.7) |
0.0 (0.0) |
8.5 (28) |
1.5 (2.7) |
0.0 (0.1) |
0.0 (0.2) |
2.2 (2.2) |
13 (27) |
376 (128) |
180 (137) |
| No SF available (8 patients) |
51 (15) |
75 (15) |
0.2 (0.6) |
0.0 (0.0) |
0.1 (0.2) |
0.1 (0.2) |
0.1 (0.2) |
14 (29) |
16 (44) |
14 (29) |
371 (229) |
276 (288) |
Pre-treatment clinical OA and baseline serum characteristics (mean +/- SD) of patients whose synovial fluid were analysed, were similar to those of patients whose synovial fluid were not analysed due to insufficient amounts of SF in the knee at time of aspiration.
KOOS, Knee and Osteoarthritis Outcome Score; KSCRS, Knee Society Clinical Rating Scale; SF, synovial fluid; OA, osteoarthritis; IL-4, interleukin-4; IL-6, interleukin-6; IL-10, interleukin-10; IL-13, interleukin-13; IFN-γ, interferon gamma; OSM, oncostatin M; TNF-α, tumor necrosis factor alpha; OPG, osteoprotegerin; IL-1ra, interleukin-1 receptor antagonist.