Table 4.
Overlap between erythropoiesis signature and cell-specific signatures
| Cell type | Probe sets in cell-specific signature a | Overlap with erythropoiesis signature b | Overlap observed c | Overlap expected d |
|---|---|---|---|---|
| CD4+ T lymphocytes | 211 | 0 | 0 | 0.9% |
| CD8+ T lymphocytes | 252 | 0 | 0 | 1.1% |
| CD14+ monocytes | 447 | 0 | 0 | 2.0% |
| CD19+ B lymphocytes | 272 | 1 | 2.0% | 1.2% |
| CD56+ NK cells | 265 | 0 | 0 | 1.2% |
| CD33+ myeloid lineage | 448 | 0 | 0 | 2.0% |
| CD34+ stem cells | 227 | 4 | 8.2% | 1.0% |
| CD105+ mesenchymal stem cells/endothelial precursors | 360 | 18 | 36.7% | 1.6% |
| CD71+ erythroid precursors | 563 | 39 | 79.6% | 2.5% |
| BDCA4+ dendritic cells | 372 | 0 | 0 | 1.7% |
aDetermined by using the HG U133A GeneChip.
bNumber relative to the 49 probe sets from the erythropoiesis signature that are present on the U133A GeneChip.
c(Number of probe sets overlapping with erythropoiesis signature)/(49(total of probe sets in the erythropoiesis signature)) × 100.
d(Number of probe sets in the signature) × (49(total of probe sets in the erythropoiesis signature))/(22,283 total of probe sets on the U133A GeneChip) × 100.