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Upregulation of A2M surface protein expression in steroid-induced early ANFH. Immunohistochemistry comparing the A2M (a, b), COL2A1 (c, d) and MIA (CD RAP) (e, f) protein expression between G1 (a, c, e) and G2 (b, d, f) WKY rats, showing enhancement of A2M expression in G2 compared to G1 but no enhancement shown for COL2A1 and MIA genes; brown color demonstrates protein expression and green color displays intact nucleus of cells, (a-d) ×40, (e, f) ×100.
