Figure 7. Phylogenetic analyses of the untranslated I domain within the nitr13 gene.

(a) The untranslated I domain encoded in the 3' untranslated region of nitr13 (termed Nitr13^P for precursor of Nitr13) is aligned with I domains from other zebrafish NITRs. Black shading indicates identical residues whereas gray shading indicates functionally similar residues. The J-related domain and residues highly conserved in Ig domains (Litman et al. 2001) are indicated above the alignment using the IMGT numbering system (Giudicelli et al. 2006). Six highly conserved cysteines, representative of NITR I domains, are indicated by asterisks below the alignment (Litman et al. 2001). (b) Phylogenetic analyses of the I domain from zebrafish Nitr13^P and I domains from the zebrafish NITR families described previously (Yoder et al. 2004). Analyses and presentation are as in Fig. 4.