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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2010 Jul 1;54(3):248–257. doi: 10.1097/qai.0b013e3181c8ef22

Table 4.

Hospitalization Rate by Primary Specific Cause1 during Study Period, 1999–2007

Cause of Hospitalization All periods 1999–2001 2002–2004 2005–2007 Relative Rate2 (95% CI) p-value

AIDS Defining Condition
 Patients hospitalized 78 33 29 24
 Total hospitalizations 133 47 49 37 0.95 (0.71–1.27) 0.72
 Rate 10.3 (8.7–12.2) 10.9 (8.2–14.5) 10.8 (8.2–14.3) 9.0 (6.5–12.4)

Infection
 Patients hospitalized 401 171 166 139
 Total hospitalizations 637 230 226 181 0.94 (0.84–1.05) 0.27
 Rate 49.2 (45.5–53.2) 53.4 (46.9–60.8) 49.9 (43.8–56.9) 44.0 (38.1–50.9)

MRSA 3
 Patients hospitalized 13 1 2 10
 Total hospitalizations 21 2 4 15 3.19 (1.10–9.20) 0.03
 Rate 1.6 (1.1–2.5) 0.5 (0.1–1.9) 0.9 (0.3–2.4) 3.6 (2.2–6.1)

Skin/Soft Tissue Infection
 Patients hospitalized 71 17 26 31
 Total hospitalizations 94 21 30 43 1.50 (1.07–2.09) 0.02
 Rate 7.3 (5.9–8.9) 4.9 (3.2–7.5) 6.6 (4.6–9.5) 10.5 (7.8–14.1)

Pneumonia
 Patients hospitalized 84 37 32 26
 Total hospitalizations 108 42 36 30 0.91 (0.70–1.18) 0.47
 Rate 8.3 (6.9–10.1) 9.8 (7.2–13.2) 8.0 (5.7–17.0) 7.3 (5.1–10.4)

Liver Disease 4
 Patients hospitalized 21 4 14 7
 Total hospitalizations 34 5 17 12 1.71 (1.03–2.83) 0.04
 Rate 2.6 (1.9–3.7) 1.2 (0.5–2.8) 3.8 (2.3–6.0) 2.9 (1.7–5.1)

Chronic End-Organ Disease 5
 Patients hospitalized 107 41 47 33
 Total hospitalizations 161 48 68 45 1.02 (0.94–1.10) 0.62
 Rate 12.4 (10.7–14.5) 11.1 (8.4–14.8) 15.0 (11.8–19.0) 10.9 (8.2–14.7)

Surgery, Primary Reason
 Patients hospitalized 218 70 85 91
 Total hospitalizations 283 75 107 101 1.17 (1.01–1.35) 0.04
 Rate 21.9 (19.5–24.6) 17.4 (13.9–21.8) 23.6 (19.6–28.6) 24.6 (20.2–29.2)

Surgery, Any 6
 Patients hospitalized 310 104 131 126
 Total hospitalizations 424 115 162 147 1.14 (1.01–1.29) 0.03
 Rate 32.7 (29.8–36.0) 26.7 (22.2–32.1) 35.8 (30.7–41.7) 35.8 (30.4–42.0)

Drug-Related 7
 Patients hospitalized 34 16 10 12
 Total hospitalizations 47 20 12 15 0.89 (0.59–1.35) 0.59
 Rate 3.6 (2.7–4.8) 4.6 (3.0–7.2) 2.7 (1.5–4.7) 3.6 (2.2–6.1)

Suicide Attempt
 Patients hospitalized 19 7 7 6
 Total hospitalizations 20 7 7 6 0.96 (0.56–1.64) 0.87
 Rate 1.5 (1.0–2.4) 1.6 (0.8–3.4) 1.5 (0.7–3.2) 1.5 (0.7–3.2)

Trauma/Injury-Related
 Patients hospitalized 37 19 13 6
 Total hospitalizations 41 22 13 6 0.54 (0.35–0.83) <0.01
 Rate 3.2 (2.3–4.3) 5.1 (3.4–7.8) 2.9 (1.7–4.9) 1.5 (0.7–3.2)
1

Rates per 1,000 person-years. Rates are unadjusted and based on clinically relevant diagnoses which were not mutually exclusive from the organ and disease categories presented in Table 3.

2

RR are estimated changes from one time interval to the next

3

MRSA was based on positive culture confirmation

4

Liver disease defined as an admission due to cirrhosis, hepatitis B, C, or other any other form of hepatitis

5

Chronic end-organ diseases included chronic obstructive lung disease, asthma, congestive heart failure, cardiomyopathy, arrhythmia, coronary artery disease, cerebrovascular disease, hypertension, pancreatitis, chronic liver disease, and chronic renal disease

6

Surgery performed during hospitalization regardless if it was the primary reason for admission

7

Drug-related defined as alcohol or illicit drug use or an overdose as the cause of admission