Table 6.

Multivariate Analyses of Factors Associated with Hospitalization

	All Hospitalizations		Non-AIDS-Defining		Infectious Cause		Primary Surgical
Factor	RR (95% CI)	p-value	RR (95% CI)	p-value	RR (95% CI)	p-value	RR (95% CI)	p-value
Age, per 10 years	1.08 (0.98–1.19)	0.12	1.11 (1.00–1.21)	0.05	0.96 (0.83–1.11)	0.60	1.25 (1.06–1.48)	<0.01
Gender, female vs. male	1.34 (0.99–1.80)	0.05	1.38 (1.04–1.83)	0.02	0.71 (0.40–1.24)	0.22	1.49 (0.95–2.35)	0.08
Race/ethnicity
African American vs. Caucasian	0.88 (0.73–1.06)	0.18	0.85 (0.71–1.02)	0.09	1.09 (0.86–1.39)	0.48	0.58 (0.41–0.81)	<0.01
Other vs. Caucasian	1.01 (0.76–1.32)	0.99	0.97 (0.74–1.27)	0.84	0.95 (0.59–1.51)	0.82	0.82 (0.50–1.34)	0.42
Chronic hepatitis B	1.19 (0.82–1.71)	0.36	1.23 (0.86–1.76)	0.26	1.21 (0.80–1.81)	0.37	1.31 (0.79–2.17)	0.30
Chronic hepatitis C	1.46 (1.05–2.03)	0.02	1.57 (1.13–2.20)	<0.01	0.97 (0.66–1.43)	0.87	1.59 (0.99–2.55)	0.06
Nadir1 CD4 count, per 50 cells/mm3	0.92 (0.89–0.95)	<0.01	0.94 (0.91–0.97)	<0.01	0.86 (0.82–0.91)	<0.01	1.03 (0.98–1.09)	0.28
Proximal CD4 count
350–499 vs. <350	0.71 (0.59–0.86)	<0.01	0.75 (0.62–0.91)	<0.01	0.67 (0.51–0.89)	<0.01	0.92 (0.60–1.41)	0.69
≥500 vs. <350	0.67 (0.56–0.81)	<0.01	0.70 (0.58–0.84)	<0.01	0.56 (0.44–0.72)	<0.01	0.82 (0.54–1.25)	0.36
Receipt of HAART 2
At CD4 <350	0.72 (0.55–0.94)	0.02	0.73 (0.54–0.97)	0.03	0.62 (0.45–0.84)	<0.01	1.71 (0.69–4.22)	0.25
At CD4 350–499	0.81 (0.53–1.24)	0.33	0.81 (0.52–1.26)	0.35	0.58 (0.34–0.99)	0.05	1.09 (0.50–2.37)	0.83
At CD4 ≥500	1.06 (0.79–1.41)	0.71	1.01 (0.76–1.32)	0.97	1.34 (0.85–2.10)	0.21	0.79 (0.48–1.31)	0.35
HAART × CD4 level interaction		0.13		0.30		0.07		0.13

¹Nadir represents the lowest CD4 count from HIV diagnosis through the prior year to hospitalization

²Results from separate analyses for proximal CD4 levels < 350, 350–499, and 500+ including same covariates. RR, relative rate