Table 2.

Operating characteristics with equal randomization and adaptive randomization; adaptive randomization starts at the 21st patient

Method	Arm	#{Arm} Ave(SD)	Pr(selected)	#{Success} Ave(SD)	Degree of imbalance
Scenario 1:(β0, βT, β1, β2, β3) = (0, 0, 1.3, 0.6, 0.4); pu = 0.975; pl = 0.025
ER
	A	49.86(5.04)	0.025	57.88(4.83)	0.23
	B	50.14(5.04)	0.025
CA
	A	49.99(5.80)	0.020	57.90(4.87)	0.04
	B	50.01(5.80)	0.021
RA
	A	50.19(14.78)	0.030	58.00(4.99)	0.22
	B	49.81(14.78)	0.035
RACA
	A	50.07(11.25)	0.024	57.87(4.95)	0.05
	B	49.93(11.25)	0.026
Scenario 2:(β0, βT, β1, β2, β3) = (0, 1, 1.3, 0.6, 0.4);Type I error=0.05
ER
	A	49.90(5.03)	0.00	67.48(4.70)	0.22
	B	50.10 (5.03)	0.54
CA
	A	49.99(5.80)	0.00	67.41(4.68)	0.04
	B	50.01(5.80)	0.58
RA
	A	28.46(11.44)	0.00	71.66(4.89)	0.20
	B	71.54(11.44)	0.47
RACA
	A	32.38(10.41)	0.00	70.85(4.78)	0.06
	B	67.62(10.41)	0.53
Scenario 3:(β0, βT, β1, β2, β3) = (0, 2, 1.3, 0.6, 0.4); Type I error=0.05
ER
	A	49.93(4.96)	0.00	73.78(4.30)	0.22
	B	50.07 (4.96)	0.97
CA
	A	49.94(5.84)	0.00	72.75(4.46)	0.04
	B	50.06(5.84)	0.97
RA
	A	18.06(6.87)	0.00	83.79(3.77)	0.17
	B	81.94(6.87)	0.92
RACA
	A	20.85(7.67)	0.00	82.91(3.92)	0.08
	B	79.15(7.67)	0.96