TABLE 1.

Pharmacokinetic parameters for orally administered BaP in IE-Cpr-null, liver-Cpr-null, and WT mice

Data from Fig. 1 were analyzed for determination of pharmacokinetics parameters. Values represent means ± S.D. (n = 5–6).

Experiment No.	Strain	Tmax	Cmax	t1/2	AUC0-6 h
		h	ng/ml	h	ng · h/ml
1	WT	0.92	215 ± 72	0.75 ± 0.16	352 ± 97
	IE-Cpr-null	1.66	378 ± 120*	1.57 ± 0.54**	1090 ± 410**
2	WT	1.20	234 ± 88	0.74 ± 0.31	447 ± 112
	liver-Cpr-null	1.40	251 ± 143	0.84 ± 0.32	618 ± 311

^*P < 0.05;

^**P < 0.01, compared with the WT group (Student's t test).