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. 2010 Jul;334(1):156–163. doi: 10.1124/jpet.110.167742

TABLE 2.

Pharmacokinetic parameters for intraperitoneally administered BaP in IE-Cpr-null, liver-Cpr-null, and WT mice

Data from Fig. 2 were analyzed for determination of pharmacokinetics parameters. Values represent means ± S.D. (n = 6–8).

Experiment No. Strain Tmax Cmax t1/2 AUC0-6 h
h ng/ml h ng · h/ml
1 WT 0.50 115 ± 27 3.44 ± 1.18 309 ± 64
IE-Cpr-null 0.56 119 ± 27 2.91 ± 1.05 297 ± 39
2 WT 0.50 128 ± 36 3.06 ± 0.52 336 ± 73
liver-Cpr-null 0.56 114 ± 21 2.23 ± 0.30** 355 ± 52
**

P < 0.01, compared with the WT group (Student's t test).