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. 2010 Jul;334(1):156–163. doi: 10.1124/jpet.110.167742

TABLE 3.

Pharmacokinetic parameters for orally administered BaP in BNF-pretreated mice

Data from Fig. 3B were analyzed for determination of pharmacokinetics parameters. Values represent means ± S.D. (n = 6).

Strain Tmax Cmax t1/2 AUC0-6 h
h ng/ml h ng · h/ml
WT 0.92 ± 0.20 30 ± 10 0.38 ± 0.04 54 ± 11
IE-Cpr-null 1.50 ± 0.55 129 ± 43** 1.31 ± 0.77** 380 ± 56**
**

P < 0.01, compared with WT mice (Student's t test).