TABLE 4.

Increased survival rate of xh-CL embryos

Genotype distribution was analyzed in a total of 392 pups derived from matings between female Alb-Cre(+/−)/Cpr^r-CL/+ and male Cpr^r-CL/r-CL mice. Numbers in parentheses indicate percentage of the total number of pups.

Gender	Number of Pups in Each Genotypea
	Alb-Cre(−/−)/Cprr-CL/r-CL (r-CL)	Alb-Cre(−/−)/Cprr-CL/+ (heterozygous r-CL)	Alb-Cre(+/−)Cprr-CL/r-CL (xh-CL)	Alb-Cre(+/−)Cprr-CL/+ (heterozygous xh-CL)
Female + male	75b (19.1%)	115 (29.3%)	94 (24.0%)	108 (27.6%)
Female	43	60	39	44
Male	32c	55	55d	64

^aThe number of pups in each genotype was significantly different from the 25% value, expected according to Mendelian distribution, for male pups alone (P < 0.05), or male and female combined (P < 0.05), although not for female pups alone (P > 0.05).

^bSignificantly lower than the number of corresponding heterozygous pups (P < 0.01; χ² test).

^cSignificantly lower than the number of corresponding heterozygous pups (P < 0.05; χ² test).

^dSignificantly higher than the number of corresponding r-CL pups (P < 0.05; χ² test).