TABLE 2.
Adrenocorticotropin levels at baseline and 15 min after saline injection
Units of adrenocorticotropin are pg/ml plasma. Means and S.E. were calculated by using the least-squares method in a three-way ANOVA model. There is a significant difference between males and females at baseline (P = 0.012) in all genotypes. There was also a significant effect of saline injection in males (P < 0.001) and females (P = 0.001) of all genotypes.
| Genotype | Female Mice |
Male Mice |
||||||
|---|---|---|---|---|---|---|---|---|
| Baseline |
After Saline Injection |
Baseline |
After Saline Injection |
|||||
| n | Mean (S.E.) | n | Mean (S.E.) | n | Mean (S.E.) | n | Mean (S.E.) | |
| Adcy7(+/−) | 4 | 21.7 (4.2) | 4 | 45.1 (4.2) | 7 | 11.3 (3.1) | 4 | 28.8 (4.2) |
| Wild type | 6 | 27.0 (3.4) | 8 | 34.5 (2.9) | 9 | 11.5 (2.8) | 6 | 33.0 (3.4) |
| Adcy7huTG | 6 | 23.9 (3.4) | 5 | 36.0 (3.7) | 6 | 16.8 (3.4) | 3 | 37.4 (4.8) |