Table III.
CoV of parameter estimates
Model parameter CoV | WT-cTnT | cTnTS199E/T204E | ||||
RD | NLRD | p-value | RD | NLRD | p-value | |
b CoV | 0.0196 ± 0.0004 | 0.0071 ± 0.0005 | 2.8 × 10−9 | 0.0275 ± 0.0027 | 0.0087 ± 0.0005 | 0.0001 |
c CoV | 0.0144 ± 0.0003 | 0.0061 ± 0.0003 | 3.6 × 10−9 | 0.0181 ± 0.0009 | 0.0079 ± 0.0004 | 8.3 × 10−6 |
γ CoV | — | 0.0092 ± 0.0006 | — | — | 0.0005 ± 0.0005 | — |
In all cases, the CoV of the parameter estimates were <5%, suggesting that these parameters were estimated with a high degree of confidence. Estimates are reported as mean ± SEM. CoV were less in the NLRD model, suggesting that these parameters were estimated with an even higher degree of confidence than those estimated using the RD model.