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. 2010 Aug;136(2):129–133. doi: 10.1085/jgp.201010416

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© 2010 Xie et al.

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Figure 2. — Stimulus intensity dependence of elemental calcium release mode. A weak stimulus preferentially activates rogue RYRs to produce quarky calcium release (A), whereas a strong stimulus activates the main cluster as well as the rogue RYRs (B).