Figure 4. Maximum contig size probabilities, bacterium sequencing.

Fig. 4 provides estimated and analytically determined probabilities of maximum contig sizes for genomes of 2000000 bases sequenced using 10000, 20000 and 40000 reads of length 200. The green, red and blue lines represent probabilities determined using simulations of the non-discretized and expectation overlap tiled genomes, and Eq. 1 respectively. For relatively low coverage levels Eq. 1 accurately estimates actual maximum contig size probabilities as determined by simulations of the non-discretized genome. However, it is inaccurate when the number of reads is 40000, corresponding to a 4× depth of coverage.