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TGF-α and AREG expression was significantly increased in mice treated with CCl4. (A) TGF-α, (B) HB-EGF and (C) AREG expression were determined by quantitative real-time PCR. Each value represents the mean ± SD. *P < 0.05 and **P < 0.001 compared with respective control mice (Time point I: Control group n = 4, CCl4 Group n = 4; Time point II: Control group n = 2, CCl4 Group n = 5, Time point III: Control group n = 5, CCl4 Group n = 9).
