Table 1.
Phenotype of MCcp, MCp and Mature Mast Cells (MC)
| Bone Marrow | Blood | Peritoneal Cavity | |||
|---|---|---|---|---|---|
| MCcp | MCp* | MCp | MCp | MC | |
| Antibody: | |||||
| mAb BGD6 | + | + | + | + | + |
| mAb AA4 | - | + | + | + | + |
| Anti-FcεRI | - | + | + | + | + |
| Anti-IgE | - | + | + | + | + |
| Anti c-kit | + | + | + | + | + |
| Anti-CD13 | + | + | + | + | + |
| Anti-CD34 | + | + | ND* | + | ± |
| Diameter | 3-4 μm | 3-6 μm | 3-6 μm | 3-6 μm | 10-20 μm |
*[18]
+ = > 98% of the cells are positive
± = 38% of the cells are positive
- = no immunostaining was detected
Cells were immunostained with the different antibodies in 7 different experiments. In each experiment a minimum of 500 cells per antibody were counted by fluorescence microscopy.