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. 2010 Jul 8;2:12. doi: 10.1186/2040-7378-2-12

Figure 4.

Figure 4

Effect of pretreatment with ONO-AE1-259-01 on neurologic deficit scores and infarct volume after 4 days of reperfusion. Mice were pretreated with ONO-AE1-259-01 before being subjected to 90-min MCAO and 4 days of reperfusion. (A) Images of representative TTC-stained brain sections. (B) Percent corrected cortical, striatal, and hemispheric infarct volumes. (C) Neurologic deficit scores were significantly lower in mice treated with 1.0 and 2.0 nmol ONO-AE1-259-01 than in vehicle-treated mice. n = 9/group; *P < 0.05 compared with the vehicle-treated group.