Table 1.
Physiologic Parameters in WT and EP2-/- Mice
Parameter | WT Mice | EP2-/- Mice | ||||
---|---|---|---|---|---|---|
Baseline | 1 h MCAO | 1 h Reperfusion | Baseline | 1 h MCAO | 1 h Reperfusion | |
pH | 7.37 ± 0.02 | 7.34 ± 0.02 | 7.35 ± 0.01 | 7.32 ± 0.01 | 7.33 ± 0.01 | 7.33 ± 0.01 |
PaCO2 | 38.2 ± 1.4 | 40.0 ± 1.5 | 38.7 ± 1.5 | 42.5 ± 1.3 | 41.2 ± 2.2 | 41.4 ± 1.0 |
PaO2 | 113 ± 6 | 131 ± 3 | 121 ± 9 | 127 ± 3 | 124 ± 5 | 120 ± 4 |
Measurements were made in arterial blood samples obtained via femoral catheter. WT, n = 4; EP2-/-, n = 5.