Table 4.
Niacin and ketoprofen released from CDCA-lysine-niacin and CDCA-lysine-ketoprofen, respectively in Caco-2 and liver S9 after 4 hours.
| Caco-2 | Liver S9 | |
|---|---|---|
| Percent niacin released in 1 μM CDCA-lysine-niacin | 69.4% | -a |
| Percent niacin released in 5 μM CDCA-lysine-niacin | 26.9% | - |
| Percent ketoprofen released from 1μM CDCA-lysine-ketoprofen | 5.94% | 24.5% |
| Percent ketoprofen released from 5 μM CDCA-lysine-ketoprofen | 3.73% | 12.2% |
a
Cannot be measured due to a high baseline niacin level in rat liver S9 fraction.